Lisa Timmers
PhD student
Nationality: Dutch
Undergraduate Institution: Wageningen University
Master Institution: Wageningen University
Graduate Institution: Eindhoven University of Technology
Email: e.m.timmers@tue.nl
Phone: +31 40 247 5414
Office: CE 1.44
Sub-group(s):
Biography:
To obtain my BSc degree, I studied nucleic acid guide acquisition and processing by a bacterial protein in my thesis project. Next, I completed a master’s thesis on the use of dendrimers in supramolecular nano-assemblies, in the group of Prof. Dr. Aldrik Velders. I encapsulated nanoparticles inside the dendrimers and subsequently assembled these into complex coacervate core micelles, to create a box-in-a-box system. I characterized the components and the assemblies using mainly nuclear magnetic resonance spectroscopy and dynamic light scattering. I finalized my Molecular Life Sciences MSc degree with an internship at the Australian Institute for Bioengineering and Nanotechnology, under supervision of Assoc. Prof. Idriss Blakey. I employed the ability of the surface of gold nanoparticles to enhance Raman scattering. In order to create nanosensor films, I tuned the ionic strength and the polymer stabilization of these gold nanoparticles. In 2017, I joined the Institute for Complex Molecular Systems in Eindhoven as a PhD student with Dr. Ilja Voets.
Research Interests:
In my PhD project, I study the effect of the monomer sequence on self-assembly. For this purpose, I characterize self-assembly behavior of sequence-controlled polymers using several approaches, including light scattering, X-ray scattering and surface tension measurements.
Selected publications
- Autonomous generation and loading of DNA guides by bacterial argonaute. D.C. Swarts, M. Szczepaniak, G. Sheng, S.D. Chandradoss, Y. Zhu, E.M. Timmers, et al. Molecular cell. 2017. 65 (6), 985-998.
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