Protein biophysics

Proteins are amongst the most essential components of all living matter. Cells for example contain up to 30 wt% of thousands of different types of proteins. We study the self-organization of this ‘biological soft matter’ and its effect on their functional and mechanical properties.

Current interests

  • Antifreeze proteins: from mechanism to material
  • Single-molecule localization microscopy of proteins at interfaces
  • Protein liquids
  • Thin, large area protein crystals for ultrafast electron diffraction
  • Functional and dysfunctional crystallization of proteins
  • Stability of concentrated protein mixtures
  • Intrinsically disordered proteins
  • Peptide/membrane interactions
  • Enveloped viruses